Discovery and Preclinical Characterization of the Cyclopropylindolobenzazepine BMS-791325, A Potent Allosteric Inhibitor of the Hepatitis C Virus NS5B Polymerase.
Gentles, R.G., Ding, M., Bender, J.A., Bergstrom, C.P., Grant-Young, K., Hewawasam, P., Hudyma, T., Martin, S., Nickel, A., Regueiro-Ren, A., Tu, Y., Yang, Z., Yeung, K.S., Zheng, X., Chao, S., Sun, J.H., Beno, B.R., Camac, D.M., Chang, C.H., Gao, M., Morin, P.E., Sheriff, S., Tredup, J., Wan, J., Witmer, M.R., Xie, D., Hanumegowda, U., Knipe, J., Mosure, K., Santone, K.S., Parker, D.D., Zhuo, X., Lemm, J., Liu, M., Pelosi, L., Rigat, K., Voss, S., Wang, Y., Wang, Y.K., Colonno, R.J., Gao, M., Roberts, S.B., Gao, Q., Ng, A., Meanwell, N.A., Kadow, J.F.
J.Med.Chem.