CATH Classification

Domain Context

CATH Clusters

Superfamily Transferase(Phosphotransferase) domain 1
Functional Family Ribosomal protein S6 kinase

Enzyme Information

2.7.11.1
Non-specific serine/threonine protein kinase.
based on mapping to UniProt Q15418
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.

UniProtKB Entries (1)

Q15418
KS6A1_HUMAN
Homo sapiens
Ribosomal protein S6 kinase alpha-1

PDB Structure

PDB 4NIF
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural assembly of the signaling competent ERK2-RSK1 heterodimeric protein kinase complex
Alexa, A., Gogl, G., Glatz, G., Garai, A., Zeke, A., Varga, J., Dudas, E., Jeszenoi, N., Bodor, A., Hetenyi, C., Remenyi, A.
Proc.Natl.Acad.Sci.USA