CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.70 | Alpha-Beta Plaits |
|
3.30.70.1230 | Nucleotide cyclase |
Domain Context
CATH Clusters
| Superfamily | Nucleotide cyclase |
| Functional Family | Guanylate cyclase soluble subunit beta-1 |
Enzyme Information
| 4.6.1.2 |
Guanylate cyclase.
based on mapping to UniProt Q02153
GTP = 3',5'-cyclic GMP + diphosphate.
-!- Also acts on ITP and dGTP.
|
UniProtKB Entries (1)
| Q02153 |
GCYB1_HUMAN
Homo sapiens
Guanylate cyclase soluble subunit beta-1
|
PDB Structure
| PDB | 4NI2 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Interfacial residues promote an optimal alignment of the catalytic center in human soluble guanylate cyclase: heterodimerization is required but not sufficient for activity.
Biochemistry
|
