CATH Classification

Domain Context

CATH Clusters

Superfamily FMN-linked oxidoreductases
Functional Family Heptaprenylglyceryl phosphate synthase

Enzyme Information

2.5.1.n9
Heptaprenylglyceryl phosphate synthase.
based on mapping to UniProt Q5L3C1
All-trans-heptaprenyl diphosphate + sn-glycerol 1-phosphate = diphosphate + sn-3-O-(all-trans-heptaprenyl)glycerol 1-phosphate.
-!- Part of the pathway in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales.

UniProtKB Entries (1)

Q5L3C1
PCRB_GEOKA
Geobacillus kaustophilus HTA426
Heptaprenylglyceryl phosphate synthase

PDB Structure

PDB 4NAF
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
A comprehensive analysis of the geranylgeranylglyceryl phosphate synthase enzyme family identifies novel members and reveals mechanisms of substrate specificity and quaternary structure organization.
Peterhoff, D., Beer, B., Rajendran, C., Kumpula, E.P., Kapetaniou, E., Guldan, H., Wierenga, R.K., Sterner, R., Babinger, P.
Mol.Microbiol.
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