CATH Domain 4mw5A03

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.730	Isoleucyl-tRNA Synthetase; Domain 1
	1.10.730.10	Isoleucyl-tRNA Synthetase; Domain 1

Domain Context

CATH Clusters

Superfamily	Isoleucyl-tRNA Synthetase; Domain 1
Functional Family	Methionyl-tRNA synthetase, putative

Enzyme Information

UniProtKB Entries (1)

Q38C91_TRYB2

Trypanosoma brucei brucei TREU927

Methionyl-tRNA synthetase, putative

PDB Structure

PDB	4MW5
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structures of Trypanosoma brucei Methionyl-tRNA Synthetase with Urea-Based Inhibitors Provide Guidance for Drug Design against Sleeping Sickness. Koh, C.Y., Kim, J.E., Wetzel, A.B., de van der Schueren, W.J., Shibata, S., Ranade, R.M., Liu, J., Zhang, Z., Gillespie, J.R., Buckner, F.S., Verlinde, C.L., Fan, E., Hol, W.G. Plos Negl Trop Dis