CATH Domain 4mtyA00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.10	Roll
	3.10.200	Carbonic Anhydrase II
	3.10.200.10	Alpha carbonic anhydrase

Domain Context

CATH Clusters

Superfamily	Alpha carbonic anhydrase
Functional Family	Carbonic anhydrase 2

Enzyme Information

4.2.1.1

Carbonic anhydrase.

based on mapping to UniProt P00918

H(2)CO(3) = CO(2) + H(2)O.

-!- The enzyme catalyzes the reversible hydration of gaseous CO(2) to carbonic acid, which spontaneously converts to hydrogencarbonate under neutral pH. -!- It is widespread and found in archaea, bacteria, and eukaryotes. -!- Three distinct classes exist, and appear to have evolved independently.

UniProtKB Entries (1)

P00918

CAH2_HUMAN

Homo sapiens

Carbonic anhydrase 2

PDB Structure

PDB	4MTY
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structure of a complex formed by a protein and a helical aromatic oligoamide foldamer at 2.1 a resolution. Buratto, J., Colombo, C., Stupfel, M., Dawson, S.J., Dolain, C., Langlois d'Estaintot, B., Fischer, L., Granier, T., Laguerre, M., Gallois, B., Huc, I. Angew.Chem.Int.Ed.Engl.