CATH Domain 4mqsA00

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.20	Up-down Bundle
	1.20.1070	Rhopdopsin 7-helix transmembrane proteins
	1.20.1070.10	Rhodopsin 7-helix transmembrane proteins

Domain Context

CATH Clusters

Superfamily	Rhodopsin 7-helix transmembrane proteins
Functional Family	Muscarinic acetylcholine receptor

Enzyme Information

UniProtKB Entries (1)

ACM2_HUMAN

Homo sapiens

Muscarinic acetylcholine receptor M2

PDB Structure

PDB	4MQS
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Activation and allosteric modulation of a muscarinic acetylcholine receptor. Kruse, A.C., Ring, A.M., Manglik, A., Hu, J., Hu, K., Eitel, K., Hubner, H., Pardon, E., Valant, C., Sexton, P.M., Christopoulos, A., Felder, C.C., Gmeiner, P., Steyaert, J., Weis, W.I., Garcia, K.C., Wess, J., Kobilka, B.K. Nature