CATH Domain 4mobA01

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.10	Roll
	3.10.129	Thiol Ester Dehydrase; Chain A
	3.10.129.10	Hotdog Thioesterase

Domain Context

CATH Clusters

Superfamily	Hotdog Thioesterase
Functional Family	Acyl-CoA thioesterase 12

Enzyme Information

3.1.2.1

Acetyl-CoA hydrolase.

based on mapping to UniProt Q8WYK0

Acetyl-CoA + H(2)O = CoA + acetate.

UniProtKB Entries (1)

ACO12_HUMAN

Homo sapiens

Acetyl-coenzyme A thioesterase

PDB Structure

PDB	4MOB
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structural basis for regulation of the human acetyl-CoA thioesterase 12 and interactions with the steroidogenic acute regulatory protein-related lipid transfer (START) domain. Swarbrick, C.M., Roman, N., Cowieson, N., Patterson, E.I., Nanson, J., Siponen, M.I., Berglund, H., Lehtio, L., Forwood, J.K. J.Biol.Chem.