CATH Classification

Domain Context

CATH Clusters

Superfamily Hypothetical protein af1432
Functional Family

Enzyme Information

1.13.11.78
2-amino-1-hydroxyethylphosphonate dioxygenase (glycine-forming).
based on mapping to UniProt D0E8I5
(2-amino-1-hydroxyethyl)phosphonate + O(2) = glycine + phosphate.
-!- The enzyme, characterized from a marine bacterium, is involved in a 2-aminoethylphosphonate degradation pathway.

UniProtKB Entries (1)

D0E8I5
PHNZ_UNCHF
uncultured bacterium HF130_AEPn_1
2-amino-1-hydroxyethylphosphonate dioxygenase (glycine-forming)

PDB Structure

PDB 4MLM
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure of PhnZ in complex with substrate reveals a di-iron oxygenase mechanism for catabolism of organophosphonates.
van Staalduinen, L.M., McSorley, F.R., Schiessl, K., Seguin, J., Wyatt, P.B., Hammerschmidt, F., Zechel, D.L., Jia, Z.
Proc.Natl.Acad.Sci.USA