CATH Domain 4mleA02

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.420	Nucleotidyltransferase; domain 5
	3.30.420.40	ATPase, nucleotide binding domain

Superfamily	3.30.420.40
Functional Family	Phosphotransferase

2.7.1.2

Glucokinase.

based on mapping to UniProt P35557

ATP + D-glucose = ADP + D-glucose 6-phosphate.

-!- A group of enzymes found in invertebrates and microorganisms highly specific for glucose.

HXK4_HUMAN

Homo sapiens

Glucokinase

PDB	4MLE
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Identification of a New Class of Glucokinase Activators through Structure-Based Design. Hinklin, R.J., Boyd, S.A., Chicarelli, M.J., Condroski, K.R., Dewolf, W.E., Lee, P.A., Lee, W., Singh, A., Thomas, L., Voegtli, W.C., Williams, L., Aicher, T.D. J.Med.Chem.