CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.40 | 3-Layer(aba) Sandwich | |
3.40.367 | Hexokinase; domain 1 | |
3.40.367.20 |
Domain Context
CATH Clusters
Superfamily | 3.40.367.20 |
Functional Family | Hexokinase 1 |
Enzyme Information
2.7.1.2 |
Glucokinase.
based on mapping to UniProt P35557
ATP + D-glucose = ADP + D-glucose 6-phosphate.
-!- A group of enzymes found in invertebrates and microorganisms highly specific for glucose.
|
UniProtKB Entries (1)
P35557 |
HXK4_HUMAN
Homo sapiens
Glucokinase
|
PDB Structure
PDB | 4MLE |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Identification of a New Class of Glucokinase Activators through Structure-Based Design.
J.Med.Chem.
|