CATH Classification

Domain Context

CATH Clusters

Superfamily 3.40.630.30
Functional Family Spermidine N(1)-acetyltransferase

Enzyme Information

2.3.1.57
Diamine N-acetyltransferase.
based on mapping to UniProt Q9KL03
Acetyl-CoA + an alkane-alpha,omega-diamine = CoA + an N-acetyldiamine.
-!- Acts on 1,3-diaminopropane, 1,5-diaminopentane, putrescine, spermidine (forming N(1)- and N(8)-acetylspermidine), spermine, N(1)- acetylspermidine and N(8)-acetylspermidine.

UniProtKB Entries (1)

Q9KL03
ATDA_VIBCH
Vibrio cholerae O1 biovar El Tor str. N16961
Spermidine N(1)-acetyltransferase

PDB Structure

PDB 4MJ8
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure of spermidine N-acetyltransferase from Vibrio cholerae in complex with polyamine
Filippova, E.V., Minasov, G., Shuvalova, L., Kiryukhina, O., Kuhn, M.L., Anderson, W.F.
To be Published
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