CATH Classification
Level | CATH Code | Description |
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3 | Alpha Beta |
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3.40 | 3-Layer(aba) Sandwich |
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3.40.50 | Rossmann fold |
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3.40.50.880 | Class I glutamine amidotransferase (GATase) domain |
Domain Context
CATH Clusters
Superfamily | 3.40.50.880 |
Functional Family | Phosphoribosylformylglycinamidine synthase |
Enzyme Information
6.3.5.3 |
Phosphoribosylformylglycinamidine synthase.
based on mapping to UniProt P74881
ATP + N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide + L-glutamine + H(2)O = ADP + phosphate + 2-(formamido)-N(1)-(5-phospho-D- ribosyl)acetamidine + L-glutamate.
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UniProtKB Entries (1)
P74881 |
PUR4_SALTY
Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
Phosphoribosylformylglycinamidine synthase
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PDB Structure
PDB | 4MGH |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Importance of hydrophobic cavities in allosteric regulation of formylglycinamide synthetase: insight from xenon trapping and statistical coupling analysis
Plos One
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