CATH Domain 4mf3A02

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.190	D-Maltodextrin-Binding Protein; domain 2
	3.40.190.10	Periplasmic binding protein-like II

Domain Context

CATH Clusters

Superfamily	Periplasmic binding protein-like II
Functional Family	Glutamate receptor ionotropic, kainate 1

Enzyme Information

UniProtKB Entries (1)

GRIK1_HUMAN

Homo sapiens

Glutamate receptor ionotropic, kainate 1

PDB Structure

PDB	4MF3
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	GluK1 antagonists from 6-(tetrazolyl)phenyl decahydroisoquinoline derivatives: in vitro profile and in vivo analgesic efficacy. Martinez-Perez, J.A., Iyengar, S., Shannon, H.E., Bleakman, D., Alt, A., Clawson, D.K., Arnold, B.M., Bell, M.G., Bleisch, T.J., Castano, A.M., Del Prado, M., Dominguez, E., Escribano, A.M., Filla, S.A., Ho, K.H., Hudziak, K.J., Jones, C.K., Mateo, A., Mathes, B.M., Mattiuz, E.L., Ogden, A.M., Simmons, R.M., Stack, D.R., Stratford, R.E., Winter, M.A., Wu, Z., Ornstein, P.L. Bioorg.Med.Chem.Lett.