CATH Classification

Domain Context

CATH Clusters

Superfamily Phosphorylase Kinase; domain 1
Functional Family Ribosomal protein S6 kinase

Enzyme Information

2.7.11.1
Non-specific serine/threonine protein kinase.
based on mapping to UniProt P18654
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.

UniProtKB Entries (1)

P18654
KS6A3_MOUSE
Mus musculus
Ribosomal protein S6 kinase alpha-3

PDB Structure

PDB 4MAO
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Design of reversible, cysteine-targeted Michael acceptors guided by kinetic and computational analysis.
Krishnan, S., Miller, R.M., Tian, B., Mullins, R.D., Jacobson, M.P., Taunton, J.
J.Am.Chem.Soc.