CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.8 | Helicase, Ruva Protein; domain 3 |
|
1.10.8.1080 |
Domain Context
CATH Clusters
| Superfamily | 1.10.8.1080 |
| Functional Family | N-acetylmuramic acid 6-phosphate etherase |
Enzyme Information
| 4.2.1.126 |
N-acetylmuramic acid 6-phosphate etherase.
based on mapping to UniProt P44862
(R)-lactate + N-acetyl-D-glucosamine 6-phosphate = N-acetylmuramate 6-phosphate + H(2)O.
-!- This enzyme, along with EC 2.7.1.170, is required for the utilization of anhydro-N-acetylmuramic acid in proteobacteria. -!- The substrate is either imported from the medium or derived from the bacterium's own cell wall murein during cell wall recycling. -!- Formerly EC 4.2.1.n1.
|
UniProtKB Entries (1)
| P44862 |
MURQ_HAEIN
Haemophilus influenzae Rd KW20
N-acetylmuramic acid 6-phosphate etherase
|
PDB Structure
| PDB | 4LZJ |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structure of MurNAc 6-phosphate hydrolase (MurQ) from Haemophilus influenzae with a bound inhibitor.
Biochemistry
|
