CATH Domain 4lrsB01

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.50	Rossmann fold
	3.40.50.720	NAD(P)-binding Rossmann-like Domain

Domain Context

CATH Clusters

Superfamily	NAD(P)-binding Rossmann-like Domain
Functional Family

Enzyme Information

UniProtKB Entries (1)

D1A3K8_THECD

Thermomonospora curvata DSM 43183

4-hydroxy-2-oxovalerate aldolase

PDB Structure

PDB	4LRS
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Crystal and solution structures of the bifunctional enzyme (Aldolase/Aldehyde dehydrogenase) from Thermomonospora curvata, reveal a cofactor-binding domain motion during NAD+ and CoA accommodation whithin the shared cofactor-binding site Fischer, B., Branlant, G., Talfournier, F., Gruez, A. To be Published