CATH Classification

Domain Context

CATH Clusters

Superfamily 3.10.450.50
Functional Family

Enzyme Information

5.3.3.1
Steroid Delta-isomerase.
based on mapping to UniProt P00947
A 3-oxo-Delta(5)-steroid = a 3-oxo-Delta(4)-steroid.

UniProtKB Entries (1)

P00947
SDIS_COMTE
Comamonas testosteroni
Steroid Delta-isomerase

PDB Structure

PDB 4L7K
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Use of anion-aromatic interactions to position the general base in the ketosteroid isomerase active site.
Schwans, J.P., Sunden, F., Lassila, J.K., Gonzalez, A., Tsai, Y., Herschlag, D.
Proc.Natl.Acad.Sci.USA