CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.8 | Helicase, Ruva Protein; domain 3 |
|
1.10.8.750 | Phosphoribosylformylglycinamidine synthase, linker domain |
Domain Context
CATH Clusters
| Superfamily | Phosphoribosylformylglycinamidine synthase, linker domain |
| Functional Family | Phosphoribosylformylglycinamidine synthase |
Enzyme Information
| 6.3.5.3 |
Phosphoribosylformylglycinamidine synthase.
based on mapping to UniProt P74881
ATP + N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide + L-glutamine + H(2)O = ADP + phosphate + 2-(formamido)-N(1)-(5-phospho-D- ribosyl)acetamidine + L-glutamate.
|
UniProtKB Entries (1)
| P74881 |
PUR4_SALTY
Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
Phosphoribosylformylglycinamidine synthase
|
PDB Structure
| PDB | 4L78 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Importance of hydrophobic cavities in allosteric regulation of formylglycinamide synthetase: insight from xenon trapping and statistical coupling analysis
Plos One
|