CATH Classification

Domain Context

CATH Clusters

Superfamily Cytochrome P450
Functional Family

Enzyme Information

1.14.14.133
1,8-cineole 2-endo-monooxygenase.
based on mapping to UniProt Q8VQF6
1,8-cineole + [reduced flavodoxin] + O(2) = 2-endo-hydroxy-1,8-cineole + [oxidized flavodoxin] + H(2)O.
-!- A cytochrome P450 (heme-thiolate) protein that uses a flavodoxin-like redox partner to reduce the heme iron. -!- Isolated from the bacterium Citrobacter braakii, which can use 1,8- cineole as the sole source of carbon. -!- Formerly EC 1.14.13.156.

UniProtKB Entries (1)

Q8VQF6
CINA_CITBR
Citrobacter braakii
1,8-cineole 2-endo-monooxygenase

PDB Structure

PDB 4L77
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
P450cin active site water: implications for substrate binding and solvent accessibility.
Madrona, Y., Hollingsworth, S.A., Khan, B., Poulos, T.L.
Biochemistry