CATH Classification
Level | CATH Code | Description |
---|---|---|
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3 | Alpha Beta |
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3.30 | 2-Layer Sandwich |
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3.30.1600 | SIR2/SIRT2 'Small Domain' |
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3.30.1600.10 | SIR2/SIRT2 'Small Domain' |
Domain Context
CATH Clusters
Superfamily | SIR2/SIRT2 'Small Domain' |
Functional Family | NAD-dependent deacetylase sirtuin-3, mitochondrial |
Enzyme Information
3.5.1.- |
In linear amides.
based on mapping to UniProt Q8IXJ6
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UniProtKB Entries (1)
Q8IXJ6 |
SIR2_HUMAN
Homo sapiens
NAD-dependent protein deacetylase sirtuin-2
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PDB Structure
PDB | 4L3O |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Structural Basis for Potent Inhibition of SIRT2 Deacetylase by a Macrocyclic Peptide Inducing Dynamic Structural Change
Structure
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