CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.605 | Aldehyde Dehydrogenase; Chain A, domain 1 |
|
3.40.605.10 | Aldehyde Dehydrogenase; Chain A, domain 1 |
Domain Context
CATH Clusters
| Superfamily | Aldehyde Dehydrogenase; Chain A, domain 1 |
| Functional Family | Aldehyde dehydrogenase |
Enzyme Information
| 1.2.1.5 |
Aldehyde dehydrogenase (NAD(P)(+)).
based on mapping to UniProt P30838
An aldehyde + NAD(P)(+) + H(2)O = a carboxylate + NAD(P)H.
|
UniProtKB Entries (1)
| P30838 |
AL3A1_HUMAN
Homo sapiens
Aldehyde dehydrogenase, dimeric NADP-preferring
|
PDB Structure
| PDB | 4L1O |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Discovery of indole-2,3-diones as novel class of inhibitors for ALDH isozymes.
To be Published
|
