CATH Domain 4kywA01

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.210	PvuII Endonuclease; Chain A
	3.40.210.30	Dam replacing family, catalytic PD-(D/E)XK domain

Domain Context

CATH Clusters

Superfamily	Dam replacing family, catalytic PD-(D/E)XK domain
Functional Family

Enzyme Information

3.1.21.4

Type II site-specific deoxyribonuclease.

based on mapping to UniProt P0A459

Endonucleolytic cleavage of DNA to give specific double-stranded fragments with terminal 5'-phosphates.

-!- Large group of enzymes which recognize specific short DNA sequences and cleave either within, or at a short specific distance from, the recognition site. -!- See the REBASE database for a complete list of these enzymes: http://rebase.neb.com/rebase/

UniProtKB Entries (1)

P0A459

T2D1_STRPN

Streptococcus pneumoniae TIGR4

Type-2 restriction enzyme DpnI

PDB Structure

PDB	4KYW
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structural basis of the methylation specificity of R.DpnI. Mierzejewska, K., Siwek, W., Czapinska, H., Kaus-Drobek, M., Radlinska, M., Skowronek, K., Bujnicki, J.M., Dadlez, M., Bochtler, M. Nucleic Acids Res.