CATH Classification

Domain Context

CATH Clusters

Superfamily 2.60.40.1910
Functional Family Aminopeptidase

Enzyme Information

3.4.11.7
Glutamyl aminopeptidase.
based on mapping to UniProt Q07075
Release of N-terminal glutamate (and to a lesser extent aspartate) from a peptide.
-!- Also acts on L-alpha-glutamyl-peptides. -!- Calcium-activated and generally membrane-bound. -!- Belongs to peptidase family M1.

UniProtKB Entries (1)

Q07075
AMPE_HUMAN
Homo sapiens
Glutamyl aminopeptidase

PDB Structure

PDB 4KX9
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural insights into central hypertension regulation by human aminopeptidase a.
Yang, Y., Liu, C., Lin, Y.L., Li, F.
J.Biol.Chem.
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