CATH Classification

Domain Context

CATH Clusters

Superfamily 3.40.1310.20
Functional Family

Enzyme Information

3.1.21.-
Endodeoxyribonucleases producing 5'-phosphomonoesters.
based on mapping to UniProt D0EZM8
3.6.4.12
DNA helicase.
based on mapping to UniProt D0EZM8
ATP + H(2)O = ADP + phosphate.
-!- DNA helicases utilize the energy from ATP hydrolysis to unwind double-stranded DNA. -!- Some of them unwind duplex DNA with a 3' to 5' polarity (1,3,5,8), other show 5' to 3' polarity (10,11,12,13) or unwind DNA in both directions (14,15). -!- Some helicases unwind DNA as well as RNA (4,9). -!- May be identical with EC 3.6.4.13 (RNA helicase).

UniProtKB Entries (1)

D0EZM8
NS1_HBOC1
Human bocavirus 1
Initiator protein NS1

PDB Structure

PDB 4KW3
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure of the NS1 Protein N-Terminal Origin Recognition/Nickase Domain from the Emerging Human Bocavirus.
Tewary, S.K., Zhao, H., Shen, W., Qiu, J., Tang, L.
J.Virol.
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