CATH Classification
Level | CATH Code | Description |
---|---|---|
2 | Mainly Beta | |
2.30 | Roll | |
2.30.150 | Rna Polymerase Beta Subunit; Chain: C, domain 4 | |
2.30.150.10 | DNA-directed RNA polymerase, beta subunit, external 1 domain |
Domain Context
CATH Clusters
Superfamily | DNA-directed RNA polymerase, beta subunit, external 1 domain |
Functional Family | DNA-directed RNA polymerase subunit beta |
Enzyme Information
2.7.7.6 |
DNA-directed RNA polymerase.
based on mapping to UniProt P0A8V2
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).
-!- Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. -!- Can initiate a chain de novo. -!- In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized. -!- See also EC 2.7.7.19 and EC 2.7.7.48.
|
UniProtKB Entries (1)
P00579 |
RPOD_ECOLI
Escherichia coli K-12
RNA polymerase sigma factor RpoD
|
PDB Structure
PDB | 4KN4 |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
X-ray Crystal Structures of the Escherichia coli RNA Polymerase in Complex with Benzoxazinorifamycins.
J.Med.Chem.
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