CATH Classification

Domain Context

CATH Clusters

Superfamily 2.40.10.120
Functional Family Genome polyprotein

Enzyme Information

UniProtKB Entries (2)

P26663
POLG_HCVBK
Hepatitis C virus (isolate BK)
Genome polyprotein
Q0ZNA6
Q0ZNA6_9HEPC
Hepacivirus C
NS3 protease

PDB Structure

PDB 4K8B
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Ligand bioactive conformation plays a critical role in the design of drugs that target the hepatitis C virus NS3 protease.
Laplante, S.R., Nar, H., Lemke, C.T., Jakalian, A., Aubry, N., Kawai, S.H.
J.Med.Chem.
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