CATH Domain 4k5nA05

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.25	Alpha Horseshoe
	1.25.50	Zincin-like fold
	1.25.50.10	Peptidase M1, alanyl aminopeptidase, C-terminal domain

Domain Context

CATH Clusters

Superfamily	Peptidase M1, alanyl aminopeptidase, C-terminal domain
Functional Family	M1 family aminopeptidase

Enzyme Information

3.4.11.-

Aminopeptidases.

based on mapping to UniProt O96935

UniProtKB Entries (1)

AMP1_PLAFQ

Plasmodium falciparum FcB1/Columbia

M1 family aminopeptidase

PDB Structure

PDB	4K5N
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Synthesis and Structure-Activity Relationships of Phosphonic Arginine Mimetics as Inhibitors of the M1 and M17 Aminopeptidases from Plasmodium falciparum. Kannan Sivaraman, K., Paiardini, A., Sienczyk, M., Ruggeri, C., Oellig, C.A., Dalton, J.P., Scammells, P.J., Drag, M., McGowan, S. J.Med.Chem.