CATH Domain 4k3nA01

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.220	Leucine Aminopeptidase, subunit E; domain 1
	3.40.220.10	Leucine Aminopeptidase, subunit E, domain 1

Domain Context

CATH Clusters

Superfamily	Leucine Aminopeptidase, subunit E, domain 1
Functional Family	M17 leucyl aminopeptidase

Enzyme Information

UniProtKB Entries (1)

Q8IL11_PLAF7

Plasmodium falciparum 3D7

M17 leucyl aminopeptidase

PDB Structure

PDB	4K3N
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Synthesis and Structure-Activity Relationships of Phosphonic Arginine Mimetics as Inhibitors of the M1 and M17 Aminopeptidases from Plasmodium falciparum. Kannan Sivaraman, K., Paiardini, A., Sienczyk, M., Ruggeri, C., Oellig, C.A., Dalton, J.P., Scammells, P.J., Drag, M., McGowan, S. J.Med.Chem.