CATH Domain 4jxhA02

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.1000	Arf Nucleotide-binding Site Opener; domain 2
	1.10.1000.11	Arf Nucleotide-binding Site Opener,domain 2

Domain Context

CATH Clusters

Superfamily	Arf Nucleotide-binding Site Opener,domain 2
Functional Family	Cytohesin 1

Enzyme Information

UniProtKB Entries (1)

CYH2_HUMAN

Homo sapiens

Cytohesin-2

PDB Structure

PDB	4JXH
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Fragment-based identification of a locus in the Sec7 domain of Arno for the design of protein-protein interaction inhibitors Rouhana, J., Hoh, F., Estaran, S., Henriquet, C., Boublik, Y., Kerkour, A., Trouillard, R., Martinez, J., Pugniere, M., Padilla, A., Chavanieu, A. J.Med.Chem.