CATH Domain 4jpwG01

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.170	Beta Complex
	2.170.40	HIV Envelope Protein Gp120; Chain G
	2.170.40.20	Human immunodeficiency virus 1, Gp160, envelope glycoprotein

Domain Context

CATH Clusters

Superfamily	Human immunodeficiency virus 1, Gp160, envelope glycoprotein
Functional Family

Enzyme Information

UniProtKB Entries (1)

Q0ED31_9HIV1

Human immunodeficiency virus 1

Envelope glycoprotein gp160

PDB Structure

PDB	4JPW
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Somatic mutations of the immunoglobulin framework are generally required for broad and potent HIV-1 neutralization. Klein, F., Diskin, R., Scheid, J.F., Gaebler, C., Mouquet, H., Georgiev, I.S., Pancera, M., Zhou, T., Incesu, R.B., Fu, B.Z., Gnanapragasam, P.N., Oliveira, T.Y., Seaman, M.S., Kwong, P.D., Bjorkman, P.J., Nussenzweig, M.C. Cell(Cambridge,Mass.)