CATH Domain 4jktA02

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.710	Beta-lactamase
	3.40.710.10	DD-peptidase/beta-lactamase superfamily

Domain Context

CATH Clusters

Superfamily	DD-peptidase/beta-lactamase superfamily
Functional Family	glutaminase kidney isoform, mitochondrial

Enzyme Information

3.5.1.2

Glutaminase.

based on mapping to UniProt D3Z7P3

L-glutamine + H(2)O = L-glutamate + NH(3).

UniProtKB Entries (1)

GLSK_MOUSE

Mus musculus

Glutaminase kidney isoform, mitochondrial

PDB Structure

PDB	4JKT
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Active Glutaminase C Self-assembles into a Supratetrameric Oligomer That Can Be Disrupted by an Allosteric Inhibitor. Ferreira, A.P., Cassago, A., Goncalves Kde, A., Dias, M.M., Adamoski, D., Ascencao, C.F., Honorato, R.V., de Oliveira, J.F., Ferreira, I.M., Fornezari, C., Bettini, J., Oliveira, P.S., Paes Leme, A.F., Portugal, R.V., Ambrosio, A.L., Dias, S.M. J.Biol.Chem.