CATH Classification

Domain Context

CATH Clusters

Superfamily 1.10.238.210
Functional Family Glutaminase kidney isoform, mitochondrial

Enzyme Information

3.5.1.2
Glutaminase.
based on mapping to UniProt D3Z7P3
L-glutamine + H(2)O = L-glutamate + NH(3).

UniProtKB Entries (1)

D3Z7P3
GLSK_MOUSE
Mus musculus
Glutaminase kidney isoform, mitochondrial

PDB Structure

PDB 4JKT
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Active Glutaminase C Self-assembles into a Supratetrameric Oligomer That Can Be Disrupted by an Allosteric Inhibitor.
Ferreira, A.P., Cassago, A., Goncalves Kde, A., Dias, M.M., Adamoski, D., Ascencao, C.F., Honorato, R.V., de Oliveira, J.F., Ferreira, I.M., Fornezari, C., Bettini, J., Oliveira, P.S., Paes Leme, A.F., Portugal, R.V., Ambrosio, A.L., Dias, S.M.
J.Biol.Chem.
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