CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.90 | Alpha-Beta Complex |
|
3.90.45 | Peptide Deformylase |
|
3.90.45.10 | Peptide deformylase |
Domain Context
CATH Clusters
| Superfamily | Peptide deformylase |
| Functional Family | Peptide deformylase |
Enzyme Information
| 3.5.1.88 |
Peptide deformylase.
based on mapping to UniProt Q9FV53
Formyl-L-methionyl peptide + H(2)O = formate + methionyl peptide.
-!- Requires at least a dipeptide for an efficient rate of reaction. -!- N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. -!- Differs in substrate specificity from EC 3.5.1.27 and EC 3.5.1.31.
|
UniProtKB Entries (1)
| Q9FV53 |
DEF1A_ARATH
Arabidopsis thaliana
Peptide deformylase 1A, chloroplastic/mitochondrial
|
PDB Structure
| PDB | 4JE8 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Understanding the highly efficient catalysis of prokaryotic peptide deformylases by shedding light on the determinants specifying the low activity of the human counterpart.
Acta Crystallogr.,Sect.D
|
