CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.640 | Aspartate Aminotransferase; domain 2 |
|
3.40.640.10 | Type I PLP-dependent aspartate aminotransferase-like (Major domain) |
Domain Context
CATH Clusters
| Superfamily | Type I PLP-dependent aspartate aminotransferase-like (Major domain) |
| Functional Family | Aromatic amino acid aminotransferase |
Enzyme Information
| 2.6.1.57 |
Aromatic-amino-acid transaminase.
based on mapping to UniProt P53090
An aromatic amino acid + 2-oxoglutarate = an aromatic oxo acid + L-glutamate.
-!- L-methionine can also act as donor, more slowly. -!- Oxaloacetate can act as acceptor. -!- Controlled proteolysis converts the enzyme to EC 2.6.1.1.
|
| 2.6.1.39 |
2-aminoadipate transaminase.
based on mapping to UniProt P53090
L-2-aminoadipate + 2-oxoglutarate = 2-oxoadipate + L-glutamate.
|
UniProtKB Entries (1)
| P53090 |
ARO8_YEAST
Saccharomyces cerevisiae S288C
Aromatic/aminoadipate aminotransferase 1
|
PDB Structure
| PDB | 4JE5 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystal structure of Saccharomyces cerevisiae Aro8, a putative alpha-aminoadipate aminotransferase.
Protein Sci.
|
