CATH Domain 4jcnA01

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.40	Beta Barrel
	2.40.10	Thrombin, subunit H
	2.40.10.10	Trypsin-like serine proteases

Domain Context

CATH Clusters

Superfamily	Trypsin-like serine proteases
Functional Family

Enzyme Information

3.4.21.19

Glutamyl endopeptidase.

based on mapping to UniProt P0C0Q2

Preferential cleavage: Glu-|-Xaa, Asp-|-Xaa.

-!- In appropriate buffer the specificity is restricted to Glu-|-Xaa. -!- Bonds involving bulky side-chains of hydrophobic amino acids are cleaved at a lower rate. -!- Belongs to peptidase family S1B.

UniProtKB Entries (1)

P0C0Q2

GSEA_STAES

Staphylococcus epidermidis ATCC 12228

Glutamyl endopeptidase

PDB Structure

PDB	4JCN
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Secreted proteases control autolysin-mediated biofilm growth of Staphylococcus aureus Chen, C., Krishnan, V., Macon, K., Manne, K., Narayana, S.V., Schneewind, O. J.Biol.Chem.