CATH Classification

Domain Context

CATH Clusters

Superfamily Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2
Functional Family

Enzyme Information

1.3.1.98
UDP-N-acetylmuramate dehydrogenase.
based on mapping to UniProt Q9HZM7
UDP-N-acetyl-alpha-D-muramate + NADP(+) = UDP-N-acetyl-3- O-(1-carboxyvinyl)-alpha-D-glucosamine + NADPH.
-!- NADH can to a lesser extent replace NADPH. -!- Formerly EC 1.1.1.158.

UniProtKB Entries (1)

Q9HZM7
MURB_PSEAE
Pseudomonas aeruginosa PAO1
UDP-N-acetylenolpyruvoylglucosamine reductase

PDB Structure

PDB 4JAY
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Substrate Channel Flexibility in Pseudomonas aeruginosa MurB Accommodates Two Distinct Substrates.
Chen, M.W., Lohkamp, B., Schnell, R., Lescar, J., Schneider, G.
Plos One
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