CATH Classification

Domain Context

CATH Clusters

Superfamily Diaminopimelate Epimerase; Chain A, domain 1
Functional Family 4-hydroxyproline 2-epimerase

Enzyme Information

5.1.1.8
4-hydroxyproline epimerase.
based on mapping to UniProt Q4KGU2
Trans-4-hydroxy-L-proline = cis-4-hydroxy-D-proline.
-!- Also interconverts trans-4-hydroxy-D-proline and cis-4-hydroxy-L- proline.

UniProtKB Entries (1)

Q4KGU2
4HYPE_PSEF5
Pseudomonas protegens Pf-5
4-hydroxyproline 2-epimerase

PDB Structure

PDB 4J9X
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure of the complex of a hydroxyproline epimerase (TARGET EFI-506499, PSEUDOMONAS FLUORESCENS PF-5) with trans-4-hydroxy-l-proline
Vetting, M.W., Toro, R., Bhosle, R., Al Obaidi, N.F., Morisco, L.L., Wasserman, S.R., Sojitra, S., Washington, E., Scott Glenn, A., Chowdhury, S., Evans, B., Hammonds, J., Stead, M., Hillerich, B., Love, J., Seidel, R.D., Imker, H.J., Gerlt, J.A., Almo, S.C., Enzyme Function Initiative (EFI)
To be Published