CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.90 | Alpha-Beta Complex |
|
3.90.79 | Nucleoside Triphosphate Pyrophosphohydrolase |
|
3.90.79.40 | EvaA sugar 2,3-dehydratase subunit |
Domain Context
CATH Clusters
| Superfamily | EvaA sugar 2,3-dehydratase subunit |
| Functional Family |
Enzyme Information
| 4.2.1.159 |
dTDP-4-dehydro-6-deoxy-alpha-D-glucopyranose 2,3-dehydratase.
based on mapping to UniProt O52793
dTDP-4-dehydro-6-deoxy-alpha-D-glucopyranose = dTDP-3,4-didehydro-2,6- dideoxy-alpha-D-glucose + H(2)O.
-!- The enzyme participates in the biosynthesis of several deoxysugars, including beta-L-4-epi-vancosamine, alpha-L-megosamine, L- and D-olivose, D-oliose, D-mycarose, forosamine and beta-L-digitoxose. -!- In vitro the intermediate can undergo a spontaneous decomposition to maltol.
|
UniProtKB Entries (1)
| O52793 |
EVAA_AMYOR
Amycolatopsis orientalis
DTDP-4-dehydro-6-deoxy-alpha-D-glucopyranose 2,3-dehydratase
|
PDB Structure
| PDB | 4J7G |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structure of EvaA: A Paradigm for Sugar 2,3-Dehydratases.
Biochemistry
|
