CATH Domain 4j76A02

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.240	Tyrosyl-Transfer RNA Synthetase
	1.10.240.10	Tyrosyl-Transfer RNA Synthetase

Domain Context

CATH Clusters

Superfamily	Tyrosyl-Transfer RNA Synthetase
Functional Family	Tryptophan--tRNA ligase

Enzyme Information

UniProtKB Entries (1)

Q8IDW3_PLAF7

Plasmodium falciparum 3D7

Tryptophan--tRNA ligase

PDB Structure

PDB	4J76
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Crystal structures of Plasmodium falciparum cytosolic tryptophanyl-tRNA synthetase and its potential as a target for structure-guided drug design. Koh, C.Y., Kim, J.E., Napoli, A.J., Verlinde, C.L., Fan, E., Buckner, F.S., Van Voorhis, W.C., Hol, W.G. Mol.Biochem.Parasitol.