CATH Classification

Domain Context

CATH Clusters

Superfamily 1.20.1270.420
Functional Family Serine/threonine-protein kinase TBK1

Enzyme Information

2.7.11.1
Non-specific serine/threonine protein kinase.
based on mapping to UniProt Q9UHD2
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.

UniProtKB Entries (1)

Q9UHD2
TBK1_HUMAN
Homo sapiens
Serine/threonine-protein kinase TBK1

PDB Structure

PDB 4IWQ
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure and mechanism of activation of TANK-binding kinase 1.
Larabi, A., Devos, J.M., Ng, S.L., Nanao, M.H., Round, A., Maniatis, T., Panne, D.
Cell Rep