CATH Classification

Domain Context

CATH Clusters

Superfamily Peptidoglycan recognition protein-like
Functional Family

Enzyme Information

3.5.1.28
N-acetylmuramoyl-L-alanine amidase.
based on mapping to UniProt P06653
Hydrolyzes the link between N-acetylmuramoyl residues and L-amino acid residues in certain cell-wall glycopeptides.
-!- Formerly EC 3.4.12.5, EC 3.4.17.7 and EC 3.4.19.10.

UniProtKB Entries (1)

P06653
ALYS_STRPN
Streptococcus pneumoniae TIGR4
Autolysin

PDB Structure

PDB 4IVV
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural and functional insights into peptidoglycan access for the lytic amidase LytA of Streptococcus pneumoniae.
Mellroth, P., Sandalova, T., Kikhney, A., Vilaplana, F., Hesek, D., Lee, M., Mobashery, S., Normark, S., Svergun, D., Henriques-Normark, B., Achour, A.
MBio
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