CATH Classification
Level | CATH Code | Description |
---|---|---|
2 | Mainly Beta | |
2.120 | 6 Propeller | |
2.120.10 | Neuraminidase | |
2.120.10.80 | Kelch-type beta propeller |
Domain Context
CATH Clusters
Superfamily | Kelch-type beta propeller |
Functional Family | Kelch-like ECH-associated protein 1 |
Enzyme Information
UniProtKB Entries (1)
Q14145 |
KEAP1_HUMAN
Homo sapiens
Kelch-like ECH-associated protein 1
|
PDB Structure
PDB | 4IQK |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Small molecules inhibit the interaction of Nrf2 and the Keap1 Kelch domain through a non-covalent mechanism.
Bioorg.Med.Chem.
|