CATH Classification

Domain Context

CATH Clusters

Superfamily Metal-dependent hydrolases
Functional Family

Enzyme Information

2.7.7.7
DNA-directed DNA polymerase.
based on mapping to UniProt Q9XDH5
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
-!- Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. -!- Cannot initiate a chain de novo. -!- Requires a primer which may be DNA or RNA. -!- See also EC 2.7.7.49.

UniProtKB Entries (1)

Q9XDH5
DPO3A_THEAQ
Thermus aquaticus
DNA polymerase III subunit alpha

PDB Structure

PDB 4IQJ
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure of PolIIIalpha-Tauc-DNA complex suggests an atomic model of the replisome
Liu, B., Lin, J., Steitz, T.A.
Structure