CATH Domain 4ii9A01

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.630	Aminopeptidase
	3.40.630.30	Gcn5-related N-acetyltransferase (GNAT)

Domain Context

CATH Clusters

Superfamily	3.40.630.30
Functional Family

Enzyme Information

2.3.2.10

UDP-N-acetylmuramoylpentapeptide-lysine N(6)-alanyltransferase.

based on mapping to UniProt Q9EY50

L-alanyl-tRNA(Ala) + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamyl-L- lysyl-D-alanyl-D-alanine = tRNA(Ala) + UDP-N-acetyl-alpha-D-muramoyl-L- alanyl-D-glutamyl-N(6)-(L-alanyl)-L-lysyl-D-alanyl-D-alanine.

-!- Also acts on L-seryl-tRNA(Ser).

UniProtKB Entries (1)

Q9EY50

FEMX_WEIVI

Weissella viridescens

UDP-N-acetylmuramoylpentapeptide-lysine N(6)-alanyltransferase

PDB Structure

PDB	4II9
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	The Structure of FemXWv in Complex with a Peptidyl-RNA Conjugate: Mechanism of Aminoacyl Transfer from Ala-tRNA(Ala) to Peptidoglycan Precursors Fonvielle, M., Li de La Sierra-Gallay, I., El-Sagheer, A.H., Lecerf, M., Patin, D., Mellal, D., Mayer, C., Blanot, D., Gale, N., Brown, T., van Tilbeurgh, H., Etheve-Quelquejeu, M., Arthur, M. Angew.Chem.Int.Ed.Engl.