CATH Domain 4igdA03

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.40	Beta Barrel
	2.40.10	Thrombin, subunit H
	2.40.10.10	Trypsin-like serine proteases

Domain Context

CATH Clusters

Superfamily	Trypsin-like serine proteases
Functional Family

Enzyme Information

3.4.21.-

Serine endopeptidases.

based on mapping to UniProt P48740

UniProtKB Entries (1)

MASP1_HUMAN

Homo sapiens

Mannan-binding lectin serine protease 1

PDB Structure

PDB	4IGD
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Quantitative characterization of the activation steps of mannan-binding lectin (MBL)-associated serine proteases (MASPs) points to the central role of MASP-1 in the initiation of the complement lectin pathway Megyeri, M., Harmat, V., Major, B., Vegh, A., Balczer, J., Heja, D., Szilagyi, K., Datz, D., Pal, G., Zavodszky, P., Gal, P., Dobo, J. J.Biol.Chem.