CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.10 | Ribbon |
|
2.10.70 | Complement Module; domain 1 |
|
2.10.70.10 | Complement Module, domain 1 |
Domain Context
CATH Clusters
| Superfamily | Complement Module, domain 1 |
| Functional Family | Mannan-binding lectin serine protease 1 |
Enzyme Information
| 3.4.21.- |
Serine endopeptidases.
based on mapping to UniProt P48740
|
UniProtKB Entries (1)
| P48740 |
MASP1_HUMAN
Homo sapiens
Mannan-binding lectin serine protease 1
|
PDB Structure
| PDB | 4IGD |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Quantitative characterization of the activation steps of mannan-binding lectin (MBL)-associated serine proteases (MASPs) points to the central role of MASP-1 in the initiation of the complement lectin pathway
J.Biol.Chem.
|
