CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.20 | Up-down Bundle |
|
1.20.120 | Four Helix Bundle (Hemerythrin (Met), subunit A) |
|
1.20.120.1710 |
Domain Context
CATH Clusters
| Superfamily | 1.20.120.1710 |
| Functional Family | NAD-dependent histone deacetylase SIR2 |
Enzyme Information
| 3.5.1.- |
In linear amides.
based on mapping to UniProt P06700
|
UniProtKB Entries (1)
| P11978 |
SIR4_YEAST
Saccharomyces cerevisiae S288C
Regulatory protein SIR4
|
PDB Structure
| PDB | 4IAO |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structural basis for allosteric stimulation of Sir2 activity by Sir4 binding
Genes Dev.
|
