CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.20 | Alpha-Beta Barrel |
|
3.20.20 | TIM Barrel |
|
3.20.20.190 | Phosphatidylinositol (PI) phosphodiesterase |
Domain Context
CATH Clusters
| Superfamily | Phosphatidylinositol (PI) phosphodiesterase |
| Functional Family |
Enzyme Information
| 4.6.1.13 |
Phosphatidylinositol diacylglycerol-lyase.
based on mapping to UniProt P45723
1-phosphatidyl-1D-myo-inositol = 1D-myo-inositol 1,2-cyclic phosphate + 1,2-diacyl-sn-glycerol.
-!- This enzyme is bacterial. -!- Activity is also found in animals, but this activity is due to the presence of EC 3.1.4.11. -!- Formerly EC 3.1.4.10.
|
UniProtKB Entries (1)
| P45723 |
PLC_STAAE
Staphylococcus aureus subsp. aureus str. Newman
1-phosphatidylinositol phosphodiesterase
|
PDB Structure
| PDB | 4I8Y |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
The cation-pi box is a specific phosphatidylcholine membrane targeting motif.
J.Biol.Chem.
|
