CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.930 | BirA Bifunctional Protein; domain 2 |
|
3.30.930.10 | Bira Bifunctional Protein; Domain 2 |
Domain Context
CATH Clusters
| Superfamily | Bira Bifunctional Protein; Domain 2 |
| Functional Family | Threonine--tRNA ligase |
Enzyme Information
| 6.1.1.3 |
Threonine--tRNA ligase.
based on mapping to UniProt P0A8M3
ATP + L-threonine + tRNA(Thr) = AMP + diphosphate + L-threonyl-tRNA(Thr).
|
UniProtKB Entries (1)
| P0A8M3 |
SYT_ECOLI
Escherichia coli K-12
Threonine--tRNA ligase
|
PDB Structure
| PDB | 4HWO |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Identification of bacteria-selective threonyl-tRNA synthetase substrate inhibitors by structure-based design.
J.Med.Chem.
|